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We demonstrate a highly sensitive label-free Mach-Zehnder interferometer biosensor based on silicon nitride slot waveguide. Highly sensitive Mach-Zehnder interferometer biosensor based on silicon nitride slot waveguide. Dive into the research topics of 'Highly sensitive Mach-Zehnder interferometer biosensor based on silicon nitride slot waveguide'. Avantor®, a Fortune 500 company, is a leading global provider of mission-critical products and services to customers in the biopharma, healthcare, education & government, and advanced technologies & applied materials industries. Our portfolio is used in virtually every stage of the most important research, development and production activities in the industries we serve. Our global footprint enables us to serve more than 225,000 customer locations and gives us extensive access to research laboratories and scientists in more than 180 countries.
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Furthermore, we investigated the specific detection and quantification of the methylation of DAPK (Death-associated protein kinase) gene, which is a widely used biomarker for human cancers. We have shown that methylation sequences of DAPK gene of various methylation densities (100%, 50%, and 0% of methylation sites) can be quantified and discriminated even at a concentration as low as 1 fmol/μl or 1 nM. N2 - We demonstrate a highly sensitive label-free Mach-Zehnder interferometer biosensor based on silicon nitride slot waveguide.
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